In “A Novel Hypothermic Preservation Formulation Containing SUL-138 Enables Long-Term Hypothermic Storage of Clinical-Grade CAR-T Cells”, the authors show that HPF supplementation with ROKEPIE (SUL-138) significantly improved the viability of fresh clinical-grade CAR-T cells during hypothermic storage (2–8 °C) without affecting potency, extending stability up to 72 hours.These findings underscore the potential of ROKEPIE to support more robust GMP-compliant and point-of-care CAR-T manufacturing workflows. Read Read More
Author: adminrokepie
CAR-T cells and ROKEPIE storage for several days
Read this poster presentation by A.Öner1*, N. Nooteboom2*, B. Dekkers2, A.C van der Graaf3, G. Krenning2, E. Bremer1** & B. Gareb2** about the 6-chromanol derivative SUL-238 which extends the shelf life of CAR-T cells during hypothermic storage. You can also download the poster here. Read more about adding ROKEPIE to a freezing medium on this Read More
NEW PAPER ABOUT SUL-109
There is a new manuscript available which describes the positive effect of our SUL-109 compound which is commercially available as our ROKEPIE preservation solution. This article was written by Fatima Aerts from the Hacettepe University in Ankara (Turkey). You can read the complete article on the Biology of Blood and Marrow Transplantation website. Hypothermic storage Read More
HypoThermosol and ROKEPIE compared
A direct comparison of HypoThermosol® (Biolife Solutions) and ROKEPIE (Sulfateq) was recently published in PlosONE. Freitas Robero from the group of Prof Rui Reis (CEO of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine) used both agents for their intended application: The hypothermic preservation of cells for multiple days. The authors found Read More
Development of ROKEPIE for medical device market
ROKEPIE® makes it possible to preserve cells and tissues at low temperatures (2-8 ° C). Sulfateq wants to develop ROKEPIE further into a product for clinical applications and more specifically a preservation solution for multiple applications. To make our plans possible we receive financial support from the European Regional Development Fund of the European Union.
